Diaper Rash vs Yeast Infection: How to Tell the Difference - Verywell Health

Diaper rash can easily be mistaken for a yeast infection in babies and toddlers, and vice versa. Although they look similar, diaper rash occurs when prolonged exposure to urine (pee) or feces (poop) irritates the skin. Yeast infection is caused when urine changes the acidity of the skin, allowing fungus on the skin to overgrow.

Both can be caused by wet or infrequently changed diapers.

Yeast infections can also occur in children with weakened immune systems or be caused by antibiotics that throw off the natural balance of fungus and bacteria on the skin. However, these are not factors associated with diaper rash.

This article explains the similarities and differences between a yeast infection and diaper rash. It also explains how each condition is diagnosed so that the correct treatment is used.

Verywell / Jessica Olah

What Is a Yeast Rash?

"Candidiasis" is the term that describes a yeast infection. It happens when a common skin fungus, typically Candida albicans, starts to overgrow. The overgrowth occurs when the composition of bacteria and fungus on the genitals or anus is suddenly thrown off balance.

In babies and toddlers, the imbalance can be caused by different things:

  • Wet diapers; Urine is highly acidic and can create an inhospitable environment for naturally occurring skin bacteria. By stripping away "good" bacteria, yeasts like C. albicans can fill the void and overgrow, causing infection and inflammation.
  • Weakened immune systems: A normally functioning immune system can keep the natural flora of the genitals and anus intact. Infections and illnesses can weaken the immune response and allow robust microorganisms like yeasts to overgrow.
  • Antibiotics: Antibiotics are used to treat bacterial infections. Broad-spectrum antibiotics can kill a wide range of bacteria, including "good" bacteria on the skin, providing C. albicans the opportunity to overgrow.

What Is Diaper Rash?

Diaper rash is also known as irritant diaper dermatitis. As with any form of dermatitis, diaper rash causes skin irritation that leads to areas of reddened skin (erythema) accompanied by itching, scaling, and tiny bumps.

Irritant diaper dermatitis is caused by overhydration of the skin and the trapping of moisture inside diapers. Prolonged exposure to feces is the main cause of diaper rash, but it can also occur with prolonged exposure to urine.

Certain laundry detergents can also cause diaper rash. In addition, friction caused by ill-fitting diapers or rough fabrics can cause chafing that aggravates diaper rash.

If left untreated, diaper rash can cause tiny breaks in the skin that allow bacteria or fungus to enter underlying tissue and establish a secondary infection.

How to Tell a Yeast Rash From a Diaper Rash

A diaper yeast infection can look very similar to irritant diaper dermatitis, but there are key differences.

Yeast Infection
  • Inflamed skin is shiny, cracked, or oozing

  • Appears mainly in skin folds such as the groin or between the buttocks

  • Rashes appear in well-defined patches, often with small pimple-like bumps

  • Treatment with antifungals can sometimes take weeks

Diaper Rash
  • Inflamed skin is dry, scaly, or smooth

  • Appears mainly on the buttocks where urine or feces have pooled in a diaper

  • Rash often runs along the perimeter of pooling

  • Treatment with a mild steroid cream usually works in days

Diagnosis

Diaper rash and a diaper yeast infection can usually be diagnosed with a physical exam and a review of your child's medical history. Lab tests can be performed to confirm the suspicions, but they are usually not needed.

If there is a high level of doubt (or the rash is especially severe), a skin swab can be performed to obtain cells and fluids to culture (grow) in the lab. This can differentiate between a fungal or bacterial infection and determine which antifungal or antibiotic medication is most appropriate.

Diaper Rash Treatment

Diaper rash is treated, first and foremost, by keeping the skin dry and changing diapers immediately when wet or soiled.

To treat the rash, your healthcare provider may recommend:

  • Cleaning the skin with a soft washcloth or baby wipe after removing the diaper and using a squirt bottle to gently rinse especially sensitive areas
  • Allowing the diaper area to dry for five to 10 minutes before putting on a new diaper
  • Applying an over-the-counter (OTC) zinc oxide cream like Desitin
  • Avoiding plastic pants until the rash is fully resolved
  • Using mild detergents to wash diapers and avoiding bleach

Yeast Rash Treatment

As with a diaper rash, it is important to change diapers as soon as they are wet or soiled. To treat the rash itself, your pediatrician may recommend:

  • Washing the skin gently with mild soap (but avoid baby wipes containing alcohol or propylene glycol as they can cause stinging)
  • Air-drying the diaper area for five to 10 minutes before putting on a new diaper
  • Applying an OTC topical antifungal like Mycostatin (nystatin), Lotrimin (miconazole), or Monistat (tioconazole) with every diaper change

Yeast infections usually improve within two weeks with consistent treatment. You may help speed your child's recovery by reducing their sugar intake, as yeast feeds on sugar.

Should I Use Baby Powder?

Do not use baby powder while your baby has a diaper rash. The powder can build up in the skin folds and hold moisture, making things worse.

Summary

A diaper rash is caused by prolonged exposure to feces or urine, which irritates the skin and causes a rash, mostly around the buttocks.

A diaper yeast infection can be caused when urine changes the skin acidity and allows fungus on the skin to overgrow, causing a rash primarily in skin folds.

The treatment for a diaper rash includes an OTC zinc oxide cream, while diaper yeast infection is treated with topical antifungals. Both can be prevented by changing diapers as soon as they are wet or soiled.

13 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. American Academy of Pediatrics. Common diaper rashes and treatments.

  2. Arizona Department of Health Services. Thrush/yeast diaper rash.

  3. Martin Lopez JE. Candidiasis (vulvovaginal). BMJ Clin Evid. 2015 Mar 16;2015:0815.

  4. Turner SA, Butler G. The Candida pathogenic species complex. Cold Spring Harb Perspect Med. 2014;4(9):a019778. doi:10.1101/cshperspect.a019778

  5. Teufel A, Howard B, Hu P, Carr AN. Characterization of the microbiome in the infant diapered area: Insights from healthy and damaged skin. Exp Dermatol. 2021 Oct;30(10):1409–1417. doi:10.1111/exd.14198

  6. American Academy of Pediatrics. Thrush and other Candida infections.

  7. Johns Hopkins Medicine. Diaper dermatitis.

  8. Carr AN, DeWitt T, Cork MJ. Diaper dermatitis prevalence and severity: Global perspective on the impact of caregiver behavior. Pediatr Dermatol. 2020 Jan-Feb;37(1):130–136. doi:10.1111/pde.14047

  9. American Academy of Dermatology Association. How to treat diaper rash.

  10. Alberta Health Services (Canada). Diaper rash in children: care instructions.

  11. Alberta Health Service (Canada). Yeast diaper rash in children: care instructions.

  12. Blume-Peytavi U, Kanti V. Prevention and treatment of diaper dermatitis. Pediatr Dermatol. 2018 Mar:35 Suppl 1:s19-s23. doi:10.1111/pde.13495

  13. Mohammed L, Jha G, Malasevskaia I, Goud HK, Hassan A. The interplay between sugar and yeast infections: Do diabetics have a greater predisposition to develop oral and vulvovaginal candidiasis?. Cureus. 2021 Feb 18;13(2):e13407. doi:10.7759/cureus.13407

Additional Reading
  • American Academy of Pediatrics: HealthyChildren.org. Yeast infections in girls and young women.

  • Hanna L, Cruz SA. Candida mastitis: a case report. Perm J. 2011;15(1):62-64. doi:10.7812/tpp/10-088

By Margaret Etudo
Margaret Etudo is a health writing expert with extensive experience in simplifying complex health-based information for the public on topics, like respiratory health, mental health and sexual health.

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