Tim-3 downregulation by Toxoplasma gondii infection contributes to decidual dendritic cell dysfunction - Parasites & Vectors - Parasites & Vectors

  • Tenter AM, Heckeroth AR, Weiss LM. Toxoplasma gondii: from animals to humans. Int J Parasitol. 2000;30:1217–58.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gazzonis AL, Veronesi F, Di Cerbo AR, Zanzani SA, Molineri G, Moretta I, et al. Toxoplasma gondii in small ruminants in northern Italy-prevalence and risk factors. Ann Agric Environ Med. 2015;22:62–8.

    Article  PubMed  Google Scholar 

  • Arora N, Sadovsky Y, Dermody TS, Coyne CB. Microbial vertical transmission during human pregnancy. Cell Host Microbe. 2017;21:561–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Montoya JG, Remington JS. Management of Toxoplasma gondii infection during pregnancy. Clin Infect Dis. 2008;47:554–66.

    Article  PubMed  Google Scholar 

  • Hunt JS, Robertson SA. Uterine macrophages and environmental programming for pregnancy success. J Reprod Immunol. 1996;32:1–25.

    Article  CAS  PubMed  Google Scholar 

  • Zhou Y, Fu B, Xu X, Zhang J, Tong X, Wang Y, et al. PBX1 expression in uterine natural killer cells drives fetal growth. Sci Transl Med. 2020;12:eaax1798.

    Article  CAS  PubMed  Google Scholar 

  • Chen P, Zhou L, Chen J, Lu Y, Cao C, Lv S, et al. The immune atlas of human deciduas with unexplained recurrent pregnancy loss. Front Immunol. 2021;12:689019.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li ZH, Wang LL, Liu H, Muyayalo KP, Huang XB, Mor G, et al. Galectin-9 alleviates LPS-induced preeclampsia-like impairment in rats via switching decidual macrophage polarization to M2 subtype. Front Immunol. 2019;9:3142.

    Article  PubMed  PubMed Central  Google Scholar 

  • Moffett A, Chazara O, Colucci F, Johnson MH. Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention. Reprod Biomed Online. 2016;33:763–9.

    Article  CAS  PubMed  Google Scholar 

  • Kämmerer U, Eggert AO, Kapp M, McLellan AD, Geijtenbeek TB, Dietl J, et al. Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy. Am J Pathol. 2003;162:887–96.

    Article  PubMed  PubMed Central  Google Scholar 

  • Miyazaki S, Tsuda H, Sakai M, Hori S, Sasaki Y, Futatani T, et al. Predominance of Th2-promoting dendritic cells in early human pregnancy decidua. J Leukoc Biol. 2003;74:514–22.

    Article  CAS  PubMed  Google Scholar 

  • Juretic K, Strbo N, Crncic TB, Laskarin G, Rukavina D. An insight into the dendritic cells at the maternal-fetal interface. Am J Reprod Immunol. 2004;52:350–5.

    Article  PubMed  Google Scholar 

  • Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, et al. Immunobiology of dendritic cells. Annu Rev Immunol. 2000;18:767–811.

    Article  CAS  PubMed  Google Scholar 

  • Ahmadabad HN, Salehnia M, Saito S, Moazzeni SM. Decidual soluble factors, through modulation of dendritic cells functions, determine the immune response patterns at the feto-maternal interface. J Reprod Immunol. 2016;114:10–7.

    Article  CAS  PubMed  Google Scholar 

  • Tirado-González I, Muñoz-Fernández R, Blanco O, Leno-Durán E, Abadía-Molina AC, Olivares EG. Reduced proportion of decidual DC-SIGN+ cells in human spontaneous abortion. Placenta. 2010;31:1019–22.

    Article  PubMed  Google Scholar 

  • Wang S, Chen C, Sun F, Li M, Du M, Li X, et al. Involvement of the Tim-3 pathway in the pathogenesis of pre-eclampsia. Reprod Sci. 2021;28:3331–40.

    Article  CAS  PubMed  Google Scholar 

  • Zhan S, Zheng J, Zhang H, Zhao M, Liu X, Jiang Y, et al. LILRB4 decrease on uDCs exacerbate abnormal pregnancy outcomes following Toxoplasma gondii infection. Front Microbiol. 2018;9:588.

    Article  PubMed  PubMed Central  Google Scholar 

  • Darmochwal-Kolarz D, Kludka-Sternik M, Kolarz B, Chmielewski T, Tabarkiewicz J, Rolinski J, et al. The expression of B7–H1 and B7–H4 co-stimulatory molecules on myeloid and plasmacytoid dendritic cells in pre-eclampsia and normal pregnancy. J Reprod Immunol. 2013;99:33–8.

    Article  CAS  PubMed  Google Scholar 

  • Li T, Cui L, Xu X, Zhang H, Jiang Y, Ren L, et al. The role of Tim-3 on dNK cells dysfunction during abnormal pregnancy With Toxoplasma gondii infection. Front Cell Infect Microbiol. 2021;11:587150.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, et al. Role of Tim-3 in decidual macrophage functional polarization during abnormal pregnancy with Toxoplasma gondii infection. Front Immunol. 2019;10:1550.

    Article  PubMed  PubMed Central  Google Scholar 

  • Li Z, Zhao M, Li T, Zheng J, Liu X, Jiang Y, et al. Decidual macrophage functional polarization during abnormal pregnancy due to Toxoplasma gondii: role for LILRB4. Front Immunol. 2017;8:1013.

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, et al. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol. 2005;6:1245–52.

    Article  CAS  PubMed  Google Scholar 

  • Gupta S, Thornley TB, Gao W, Larocca R, Turka LA, Kuchroo VK, et al. Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs. J Clin Invest. 2012;122:2395–404.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gleason MK, Lenvik TR, McCullar V, Felices M, O'Brien MS, Cooley SA, et al. Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9. Blood. 2012;119:3064–72.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chiba S, Baghdadi M, Akiba H, Yoshiyama H, Kinoshita I, Dosaka-Akita H, et al. Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nat Immunol. 2012;13:832–42.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wang S, Chen C, Li M, Qian J, Sun F, Li Y, et al. Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4(+)T cells. Cell Death Dis. 2019;10:15.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhang Y, Ma CJ, Wang JM, Ji XJ, Wu XY, Jia ZS, et al. Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection. PLoS ONE. 2011;6:e19664.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li YH, Zhou WH, Tao Y, Wang SC, Jiang YL, Zhang D, et al. The galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy. Cell Mol Immunol. 2016;13:73–81.

    Article  PubMed  Google Scholar 

  • Azizieh FY, Raghupathy R. IL-10 and pregnancy complications. Clin Exp Obstet Gynecol. 2017;44:252–8.

    Article  CAS  PubMed  Google Scholar 

  • Maurya N, Gujar R, Gupta M, Yadav V, Verma S, Sen P. Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton's tyrosine kinase and c-Src. J Immunol. 2014;193:3417–25.

    Article  CAS  PubMed  Google Scholar 

  • Norkina O, Dolganiuc A, Shapiro T, Kodys K, Mandrekar P, Szabo G. Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes. J Leukoc Biol. 2007;82:752–62.

    Article  CAS  PubMed  Google Scholar 

  • Zhang X, Blenis J, Li HC, Schindler C, Chen-Kiang S. Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science. 1995;267:1990–4.

    Article  CAS  PubMed  Google Scholar 

  • Monin L, Whettlock EM, Male V. Immune responses in the human female reproductive tract. Immunology. 2020;160:106–15.

    Article  CAS  PubMed  Google Scholar 

  • Erlebacher A. Immunology of the maternal-fetal interface. Annu Rev Immunol. 2013;31:387–411.

    Article  CAS  PubMed  Google Scholar 

  • Fu X, Wu B, Huang B, Zheng H, Huang S, Gan Y, et al. The correlation of Tim-3 and IFN-gamma expressions in mice infected with Toxoplasma gondii during gestation. Parasitol Res. 2015;114:125–32.

    Article  PubMed  Google Scholar 

  • Wang SC, Li YH, Piao HL, Hong XW, Zhang D, Xu YY, et al. PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy. Cell Death Dis. 2015;6:e1738.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Meggyes M, Lajko A, Palkovics T, Totsimon A, Illes Z, Szereday L, et al. Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy. Placenta. 2015;36:1153–60.

    Article  CAS  PubMed  Google Scholar 

  • Zhu XY, Zhou YH, Wang MY, Jin LP, Yuan MM, Li DJ. Blockade of CD86 signaling facilitates a Th2 bias at the maternal-fetal interface and expands peripheral CD4+CD25+ regulatory T cells to rescue abortion-prone fetuses. Biol Reprod. 2005;72:338–45.

    Article  CAS  PubMed  Google Scholar 

  • Wang J, Tao YM, Cheng XY, Zhu TF, Chen ZF, Yao H, et al. Dendritic cells derived from preeclampsia patients influence Th1/Th17 cell differentiation in vitro. Int J Clin Exp Med. 2014;7:5303–9.

    PubMed  PubMed Central  Google Scholar 

  • Vassiliadis S, Tsoukatos D, Athanassakis I. Interferon-induced class II expression at the spongiotrophoblastic zone of the murine placenta is linked to fetal rejection and developmental abnormalities. Acta Physiol Scand. 1994;151:485–95.

    Article  CAS  PubMed  Google Scholar 

  • Sun X, Xie H, Zhang H, Li Z, Qi H, Yang C, et al. B7–H4 reduction induced by Toxoplasma gondii infection results in dysfunction of decidual dendritic cells by regulating the JAK2/STAT3 pathway. Parasit Vectors. 2022;15:157.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sedlmayr P, Blaschitz A, Wintersteiger R, Semlitsch M, Hammer A, MacKenzie CR, et al. Localization of indoleamine 2,3-dioxygenase in human female reproductive organs and the placenta. Mol Hum Reprod. 2002;8:385–91.

    Article  CAS  PubMed  Google Scholar 

  • Yuasa HJ, Takubo M, Takahashi A, Hasegawa T, Noma H, Suzuki T. Evolution of vertebrate indoleamine 2,3-dioxygenases. J Mol Evol. 2007;65:705–14.

    Article  CAS  PubMed  Google Scholar 

  • Yu LL, Zhang YH, Zhao FX. Expression of indoleamine 2,3-dioxygenase in pregnant mice correlates with CD4+CD25+Foxp3+ T regulatory cells. Eur Rev Med Pharmacol Sci. 2017;21:1722–8.

    PubMed  Google Scholar 

  • Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol. 2013;34:137–43.

    Article  CAS  PubMed  Google Scholar 

  • Chang RQ, Li DJ, Li MQ. The role of indoleamine-2,3-dioxygenase in normal and pathological pregnancies. Am J Reprod Immunol. 2018;79:e12786.

    Article  PubMed  Google Scholar 

  • Miwa N, Hayakawa S, Miyazaki S, Myojo S, Sasaki Y, Sakai M, et al. IDO expression on decidual and peripheral blood dendritic cells and monocytes/macrophages after treatment with CTLA-4 or interferon-gamma increase in normal pregnancy but decrease in spontaneous abortion. Mol Hum Reprod. 2005;11:865–70.

    Article  CAS  PubMed  Google Scholar 

  • Ban Y, Chang Y, Dong B, Kong B, Qu X. Indoleamine 2,3-dioxygenase levels at the normal and recurrent spontaneous abortion fetal-maternal interface. J Int Med Res. 2013;41:1135–49.

    Article  CAS  PubMed  Google Scholar 

  • Zardoya-Laguardia P, Blaschitz A, Hirschmugl B, Lang I, Herzog SA, Nikitina L, et al. Endothelial indoleamine 2,3-dioxygenase-1 regulates the placental vascular tone and is deficient in intrauterine growth restriction and pre-eclampsia. Sci Rep. 2018;8:5488.

    Article  PubMed  PubMed Central  Google Scholar 

  • Cubro H, Kashyap S, Nath MC, Ackerman AW, Garovic VD. The role of interleukin-10 in the pathophysiology of preeclampsia. Curr Hypertens Rep. 2018;20:36.

    Article  PubMed  Google Scholar 

  • Zhang R, Zhang H, Liu X, Fu Q, Xu X, Hu X. The immunoprotective role of interleukin-10 in abnormal pregnancy outcome induced by Toxoplasma gondii infection. Gynecol Obstet Invest. 2012;73:223–9.

    Article  CAS  PubMed  Google Scholar 

  • Makris A, Xu B, Yu B, Thornton C, Hennessy A. Placental deficiency of interleukin-10 (IL-10) in preeclampsia and its relationship to an IL10 promoter polymorphism. Placenta. 2006;27:445–51.

    Article  CAS  PubMed  Google Scholar 

  • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol. 1995;13:251–76.

    Article  CAS  PubMed  Google Scholar 

  • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3:133–46.

    Article  CAS  PubMed  Google Scholar 

  • Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, Bogdan C, et al. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med. 2002;195:15–21.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Saito S, Nakashima A, Shima T, Ito M. Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy. Am J Reprod Immunol. 2010;63:601–10.

    Article  CAS  PubMed  Google Scholar 

  • Xia Q, Wei L, Zhang Y, Sheng J, Wu W, Zhang Y. Immune checkpoint receptors Tim-3 and PD-1 regulate monocyte and T lymphocyte function in septic patients. Mediators Inflamm. 2018;2018:1632902.

    Article  PubMed  PubMed Central  Google Scholar 

  • Adblock test (Why?)

    Comments

    Popular posts from this blog